RESEARCH AND APPLICATION OF MINE-USED COOLING WATER TOWER BASED ON COUNTERFLOW CLOSED HEAT EXCHANGE PRINCIPLE


Do consanguineous parents of a child affected by an autosomal recessive disease have more DNA identical-by-descent than similarly-related parents with healthy offspring? Design of a case-control study

Abstract Background The offspring of consanguineous relations have an increased risk of congenital/genetic disorders and early mortality.Consanguineous couples and their offspring account for approximately 10% of the global population.The increased risk for congenital/genetic disorders is most marked for autosomal recessive disorders and depends on

read more

Transmembrane Helices Are an Over-Presented and Evolutionarily Conserved Source of Major Histocompatibility Complex Class I and II Epitopes

Cytolytic T cell responses are predicted to be biased towards membrane proteins.The peptide-binding grooves of most alleles of histocompatibility complex class I (MHC-I) are relatively hydrophobic, therefore peptide fragments derived from human transmembrane helices (TMHs) are predicted to be presented more often as would be expected based on their

read more